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PFEPfizer Inc. — stock analysis & sentiment

NYSEHealthcareDrug Manufacturers - General
$28.72

Last analyzed · v2

Sentiment+28·positive

Pfizer Inc. (PFE) last closed at $28.72, near the top of its 52-week range of $23.62–$29.21. Composite market sentiment across 2 analyses is positive (+28 on a −100 to +100 scale), as of Sep 29, 2026.

Produced by the Synoptiv Research Engine from public financial data. Read the methodology.

Full report

Go beyond the overview

The thesis, technical signals, risk levels, and complete evidence — everything the overview leaves out.

What changed

Since the previous analysis (v1) on Aug 6, 2026.

Price
+9.62%

PFE rose to $28.72, from $26.20 at the previous analysis.

Sentiment▲ +4
+28

Composite sentiment ticked up from +24 to +28, still positive.

News flow
51 new

51 headlines since the last analysis — 9 positive, 1 negative, 41 neutral.

Market cap+11.28%
$163.69B

Market cap rose +11.28%, from $147.1B to $163.69B.

The written analysis on this page was refreshed for v2.

What the data says

An overview of the public data behind PFE.

At $28.72, Pfizer is trading close to the top of its 52-week range of $23.62 to $29.21 — roughly 2% below the high and about 22% above the low. That range is fairly narrow for a full year, spanning less than a quarter of the stock's own value, and the current close sits in the upper portion of it, so the past twelve months have been a relatively contained band rather than a wide swing.

The market is valuing the roughly $164 billion business at about 1.9 times book value and 37.8 times trailing earnings, but only 9.9 times forward earnings — a wide gap between the two multiples, which reflects expectations for a materially different earnings base ahead than the one just reported. Reported profitability is modest against that trailing figure, with a net margin near 6.8% and revenue growth of about 2.6%. The dividend yield of roughly 6% is a large share of the total return equation here, and a beta of 0.30 indicates the shares have moved far less than the broad market, closer to a third of its typical swing.

Recent coverage has been light on company-specific developments and weighted toward the wider sector. The headlines center on other drug developers — an early-stage immuno-oncology trial start at Arvinas, analyst positioning on Alnylam — alongside industry-level market forecasts for enzyme replacement therapy and autoimmune therapeutics, and commentary on AI in vaccine adjuvant research. The item closest to Pfizer's own situation is macro rather than corporate: discussion of what a higher-for-longer interest rate path would mean for large-cap pharmaceutical dividend payers, a category this stock's yield places it in.

Written from public market data. Research, not financial advice — the thesis, signals and risk levels are in the full report.

Price chart

PFE daily price history.

Market sentiment

A composite of the public market data in this analysis, from −100 (bearish) to +100 (bullish).

BearishBullish
+28
positive

This gauge blends news tone, analyst views, insider and congressional activity, and price momentum into a single score. The full report breaks down each driver and pairs it with the thesis.

See the full sentiment breakdown in the report →

Key stats

A public snapshot of commonly used market and valuation measures.

52-week range$28.72
$23.62$29.21
Current price $28.72 sits 91% of the way between the 52-week low of $23.62 and high of $29.21.

Valuation & size

Profitability & growth

Price & risk

From noise to signal. The full report has PFE’s thesis, trade signal, and risk levels.

About Pfizer Inc.

Pfizer Inc. is a biopharmaceutical company that discovers, develops, manufactures, and sells medicines and vaccines in the United States and internationally. Founded in 1849 and headquartered in New York, it organizes its business around biopharmaceutical operations alongside smaller units covering contract manufacturing and services for external innovators. Its portfolio spans several therapeutic areas: cardiovascular and metabolic treatments including Eliquis; migraine treatments such as Nurtec ODT and Zavzpret; vaccines including the Prevnar family, Abrysvo, Trumenba, and Nimenrix; and Paxlovid for COVID-19. In inflammation and immunology it markets Xeljanz, Enbrel, Cibinqo, and others, and in rare disease it covers amyloidosis, hemophilia, and endocrine conditions through the Vyndaqel family, BeneFIX, Genotropin, and related products. Oncology is a substantial part of the business, spanning antibody-drug conjugates, small molecules, and immunotherapies — among them Ibrance, Xtandi, Padcev, Adcetris, and Talzenna — for breast, genitourinary, lung, and other cancers. Pfizer also supplies biosimilars and sterile injectables, and works through collaborations with partners including Bristol-Myers Squibb, Astellas, Merck KGaA, and BioNTech.

Healthcare · Drug Manufacturers - General

Latest news

Recent headlines related to PFE, with vendor tone.

PFE — frequently asked questions

Answered from the public data on this page.

What is the current market sentiment for PFE?

As of Sep 29, 2026, Pfizer Inc. (PFE) carries positive (+28 on a −100 to +100 scale) composite sentiment. The score fuses recent news tone, analyst recommendations, technical posture, insider and congressional activity, and market attention into a single figure. The full breakdown of each component is in the report.

How has PFE stock been performing?

Pfizer Inc. last closed at $28.72, near the top of its 52-week range of $23.62–$29.21.

What is PFE's market cap and valuation?

Pfizer Inc. has a market capitalization of about $163.69B, a trailing P/E of 37.8, a dividend yield of 6.00%.

What sector is PFE in, and who are its competitors?

Pfizer Inc. operates in the Healthcare sector, specifically Drug Manufacturers - General. Comparable companies include LLY, JNJ, MRK, BMY, RPRX.

Where can I find a full analysis of PFE?

The full PFE report covers the bull and bear cases, technical signals with entry, stop and target levels, complete financial statements, earnings history, insider and congressional trades, and the conditions that would invalidate the thesis. It requires a free account.

Analysis history

Every saved analysis, newest first.